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KMID : 1145120180160030309
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Asian Journal of Beauty and Cosmetology
2018 Volume.16 No. 3 p.309 ~ p.320
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Determination of Anti-oxidative and Whitening Effects of Complex Extracts Obtained from Sprout Panax ginseng C.A. Meyer and Cassia nomame (Sieb.) Honda on Skin
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Kim Geon-Woo
Choi Yun-Hee
Kim Byung-Loc
Kim Yong-Uk
Seong Rack-Seon
Han Min-Hee
Kim Gyeong-Ae
Choi Min-Ju
Jeong Yong-Gi
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Abstract
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Purpose: In this study, we tried to develop differentiated natural cosmetic materials through the standardization of optimal raw materials, and demonstrate complex functionality with anti-oxidative and whitening effects of natural extracts of sprout Panax ginseng C.A. Meyer and Cassia nomame (Sieb.) Honda.
Method: In this experiment, the research materials, sprout Panax ginseng C.A. Meyer and Cassia nomame (Sieb.) Honda, were prepared by identification of genetic analysis, complex extracts of sprout Panax ginseng C.A. Meyer and Cassia nomame (Sieb.) Honda were determined to have optimum anti-oxidative and whitening effects by studying the mixture ratio, solvent ratio, extraction temperature, and extraction time. The standard compound was prepared from the final complex extract.
Results: The mixture ratio of sprout Panax ginseng C.A. Meyer and Cassia nomame (Sieb.) Honda with optimum anti-oxidative and whitening effects was 1:9, extraction solvent was 30% ethanol, extraction temperature was 80℃ and extraction time was 8 h. The antioxidative activity of the complex extract showed 49.6% 1.1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity at 500 μg/mL. In a tyrosinase inhibitory activity assessment, the complex extract showed 109% tyrosinase inhibitory activity at 2,000 μg/mL. The standard compound was confirmed to be Schaftoside.
Conclusion: This study reveals key conditions for the standardization of manufacturing process to obtain optimal anti-oxidative and whitening effects from complex extracts of sprout Panax ginseng C.A. Meyer and Cassia nomame (Sieb.) Honda. We expect that the use of industrial cosmetics as raw materials for cosmetics, including Shaftoside, will not be hampered by limitations in industrial use due to international patent disputes and high costs.
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KEYWORD
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Sprout Panax ginseng C.A. Meyer, Cassia nomame (Sieb.) Honda, Antioxidative, Whitening, Schaftoside
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